US Study Reveals Slighter Link Between Autism and Drinking Water Contaminants
A new study published in the journal JAMA Pediatrics has found a moderate correlation between lithium levels in tap water and an increased risk of autism spectrum disorder (ASD) in children born to mothers exposed during pregnancy. However, experts caution that the association does not necessarily imply a direct causal link.
According to the researchers, who focused on Denmark due to its low consumption of bottled water, the level of lithium in drinking water was similar to that in US systems. The study found that as lithium levels in water increased, there was a modestly higher risk of an ASD diagnosis among children born to pregnant women exposed during pregnancy.
The findings indicate that mothers who consumed more tap water with higher levels of lithium during their pregnancies had a 24% to 26% higher risk of having a child diagnosed with ASD compared to those at lower exposure levels. The group with the highest level of lithium exposure had a 46% higher risk than those at lower exposure levels.
Despite these results, study co-author Dr. Beate Ritz emphasized that more research is required to confirm the association and determine whether there's a causal link between lithium exposure and ASD. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said.
Ritz noted that replicating the findings in other countries would be essential to validate the association, as studies have shown mixed results regarding environmental exposures to pesticides, air pollution, and phthalates in relation to ASD.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, pointed out that research on lithium exposure in pregnant women taking medication for mental health disorders has not shown a correlation with autism spectrum disorder.
"It's an interesting association, but causation is definitely not proven," Wiznitzer said. "We have to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this."
The study's findings highlight the need for further research into potential environmental factors contributing to ASD, particularly those related to drinking water contaminants.
A new study published in the journal JAMA Pediatrics has found a moderate correlation between lithium levels in tap water and an increased risk of autism spectrum disorder (ASD) in children born to mothers exposed during pregnancy. However, experts caution that the association does not necessarily imply a direct causal link.
According to the researchers, who focused on Denmark due to its low consumption of bottled water, the level of lithium in drinking water was similar to that in US systems. The study found that as lithium levels in water increased, there was a modestly higher risk of an ASD diagnosis among children born to pregnant women exposed during pregnancy.
The findings indicate that mothers who consumed more tap water with higher levels of lithium during their pregnancies had a 24% to 26% higher risk of having a child diagnosed with ASD compared to those at lower exposure levels. The group with the highest level of lithium exposure had a 46% higher risk than those at lower exposure levels.
Despite these results, study co-author Dr. Beate Ritz emphasized that more research is required to confirm the association and determine whether there's a causal link between lithium exposure and ASD. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said.
Ritz noted that replicating the findings in other countries would be essential to validate the association, as studies have shown mixed results regarding environmental exposures to pesticides, air pollution, and phthalates in relation to ASD.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, pointed out that research on lithium exposure in pregnant women taking medication for mental health disorders has not shown a correlation with autism spectrum disorder.
"It's an interesting association, but causation is definitely not proven," Wiznitzer said. "We have to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this."
The study's findings highlight the need for further research into potential environmental factors contributing to ASD, particularly those related to drinking water contaminants.