Lithium levels in drinking water have been found to be associated with a slightly higher risk of autism spectrum disorder (ASD) diagnosis in children. Researchers in Denmark conducted a study that measured the concentration of lithium in 151 public waterworks and mapped out where pregnant people lived in relation, comparing it to a database of 8,842 cases of ASD.
The results showed that as lithium levels in water increased, so did the risk of ASD diagnosis in children. Specifically, those who had the second and third highest exposure during pregnancy had a 24% to 26% higher risk of ASD diagnosed, while those with the highest exposure had a 46% higher risk than those at the lowest level of exposure.
However, experts caution that this association does not necessarily mean that lithium exposure leads directly to an autism diagnosis. Dr. Beate Ritz, co-author of the study and professor of neurology and epidemiology, emphasizes that further research is needed to confirm this finding.
"The wisdom of Solomon will be required to develop guidelines for lithium in drinking water that are maximally protective of the entire population," said Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School.
Other studies have suggested connections between ASD and environmental exposures to things like pesticides, air pollution, and phthalates. However, none of them has identified any direct cause of the disorder.
Dr. Max Wiznitzer, director of the Rainbow Autism Center, notes that research on the effects of lithium on pregnant people who take it for mental health disorders shows no connection with ASD. "It's an interesting association, but causation is definitely not proven," he said.
The study's findings highlight the need for more research into environmental factors and their potential impact on human development. As Wiznitzer noted, "We are bombarded with a variety of environmental stressors in our everyday lives. We have to figure out how to basically safely navigate them, and this is probably not one that's high on our list."
The implications of the study's findings for public health policy are complex, with some arguing that lithium levels in water may be associated with lower rates of hospitalization for psychiatric disorders and suicide.
In conclusion, while the study suggests a possible link between lithium exposure and autism diagnosis, further research is needed to confirm this finding and understand its potential implications for human health.
The results showed that as lithium levels in water increased, so did the risk of ASD diagnosis in children. Specifically, those who had the second and third highest exposure during pregnancy had a 24% to 26% higher risk of ASD diagnosed, while those with the highest exposure had a 46% higher risk than those at the lowest level of exposure.
However, experts caution that this association does not necessarily mean that lithium exposure leads directly to an autism diagnosis. Dr. Beate Ritz, co-author of the study and professor of neurology and epidemiology, emphasizes that further research is needed to confirm this finding.
"The wisdom of Solomon will be required to develop guidelines for lithium in drinking water that are maximally protective of the entire population," said Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School.
Other studies have suggested connections between ASD and environmental exposures to things like pesticides, air pollution, and phthalates. However, none of them has identified any direct cause of the disorder.
Dr. Max Wiznitzer, director of the Rainbow Autism Center, notes that research on the effects of lithium on pregnant people who take it for mental health disorders shows no connection with ASD. "It's an interesting association, but causation is definitely not proven," he said.
The study's findings highlight the need for more research into environmental factors and their potential impact on human development. As Wiznitzer noted, "We are bombarded with a variety of environmental stressors in our everyday lives. We have to figure out how to basically safely navigate them, and this is probably not one that's high on our list."
The implications of the study's findings for public health policy are complex, with some arguing that lithium levels in water may be associated with lower rates of hospitalization for psychiatric disorders and suicide.
In conclusion, while the study suggests a possible link between lithium exposure and autism diagnosis, further research is needed to confirm this finding and understand its potential implications for human health.